The Ketchikan Federal Building is a courthouse of the United States District Court for the District of Alaska, located at 648 Mission Street in Ketchikan, Alaska. It was completed in 1938, and was listed on the National Register of Historic Places on April 28, 2006. The building's primary tenant is the United States Forest Service Tongass National Forest Supervisor's Office, which occupies space on the first, second, third, fourth and sixth floors. The fifth floor houses a courtroom and related support offices, while the first floor also houses an office of the United States Customs and Border Protection.