Minnesota State Highway 60 (MN 60) is a highway in southern Minnesota, which runs from Iowa Highway 60 at the Iowa state line (at Bigelow) and continues east-northeast to its eastern terminus at the Wisconsin state line (at Wabasha), where the route becomes Wisconsin Highway 25 upon crossing the Mississippi River. Highway 60 is the only state highway in Minnesota which runs from one border to another. The route runs in a general southwest-to-northeast direction.