Nilutamide
Nilutamide (brand names Nilandron (US), Anandron (CA)) is a synthetic, non-steroidal antiandrogen (NSAA) used in the treatment of advanced-stage (metastatic) prostate cancer. It was developed by Roussel, first introduced in 1987 (in Europe) and was the second NSAA to be marketed, with flutamide preceding it and bicalutamide following it in 1995. It was not introduced until 1996 in the United States. Because most prostate cancer cells rely on activation of the androgen receptor (AR) for growth and survival, nilutamide can slow the progression of the disease and extend life in men with prostate cancer.
product
primaryTopic
Nilutamide
Nilutamide (brand names Nilandron (US), Anandron (CA)) is a synthetic, non-steroidal antiandrogen (NSAA) used in the treatment of advanced-stage (metastatic) prostate cancer. It was developed by Roussel, first introduced in 1987 (in Europe) and was the second NSAA to be marketed, with flutamide preceding it and bicalutamide following it in 1995. It was not introduced until 1996 in the United States. Because most prostate cancer cells rely on activation of the androgen receptor (AR) for growth and survival, nilutamide can slow the progression of the disease and extend life in men with prostate cancer.
has abstract
Nilutamide (brand names Niland ...... totoxicity) in choice of NSAA.
@en
Nilutamide è un farmaco orale ...... terazione con il testosterone.
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ATC prefix
ATC suffix
CAS number
63612-50-0
DrugBank
FDA UNII code
51G6I8B902
IUPAC name
5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione
@en
PubChem
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Link from a Wikipage to an external page
Wikipage page ID
Wikipage revision ID
743,975,159
bioavailability
ChEMBL
ChemSpiderID
elimination half-life
-313200.0
IUPHAR ligand
legal status
MedlinePlus
metabolites
At least 5, some active
molecular weight
3.17221e+2
pronounce
nye-LOO-tah-mide
protein bound
routes of administration
smiles
StdInChIKey
XWXYUMMDTVBTOU-UHFFFAOYSA-N
synonyms
tradename
Nilandron, Anandron
verifiedrevid
462,261,036
Watchedfields
subject
hypernym
comment
Nilutamide (brand names Niland ...... e in men with prostate cancer.
@en
Nilutamide è un farmaco orale ...... terazione con il testosterone.
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label
Nilutamide
@en
Nilutamide
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