Serpentine Gorge is one of the gorges in the West MacDonnell Ranges in Australia's Northern Territory. It is located approximately 100 kilometres west of Alice Springs along the Larapinta Trail. It comprises two gorges created by a south flowing creek which has cut through two ridges of Heavitree Quartzite. The gorge is home to some rare Central Australian plants such as the Centralian flannel-flower and cycads (the Macrozamia macdonnellii). There is a semi-permanent waterhole guarding the entrance to the gorge.