St James Street is a historic street in the town centre of Monmouth, Monmouthshire, Wales. It appears as a segment of Whitecross Street on the 1610 map of the town by cartographer John Speed and is within the medieval town walls. On more recent maps, it extends from St James Square southwest to Almshouse Street. In 2010, the street was the site of discovery of Mesolithic era artefacts. St James Street is lined with numerous listed buildings.