"Those Damned Blue-Collar Tweekers" is the third single from Primus's 1991 album Sailing the Seas of Cheese. Unlike its preceding singles "Jerry Was a Race Car Driver" and "Tommy the Cat", "Tweekers" did not feature an accompanying video. The song opens with Larry LaLonde on guitar and a reserved bassline from Les Claypool, from there alternating between his trademark slap bass and a quiet section for the vocals.