University High School of Science and Engineering (UHSSE) is a Science, Technology, Engineering, and Math magnet high school located in Hartford, Connecticut. This public school was started in 2004, with a small body of faculty, headed by principal Elizabeth Colli, and a freshman class of one hundred students. The school has changed locations since its inception. It was previously located on the Asylum campus of the University of Hartford on Elizabeth Street in Hartford, but is now in a brand new facility on Mark Twain Drive on the main campus in Hartford.