West Virginia Route 152 is a north–south state highway extending from Crum to Huntington, West Virginia. The northern terminus of WV 152 is unusual in that it also serves as the southern terminus of West Virginia Route 527, which continues along the same street as it passes over Interstate 64 at exit 8 (both state routes are indicated on exit signage on the expressway). WV 527 continues along the former routing of U.S. Route 52 through downtown Huntington, West Virginia on its way toward Chesapeake, Ohio. The southern terminus of the route is at US 52 northeast of Crum.