11-Ketoprogesterone
11-Ketoprogesterone (brand name Ketogestin; former developmental code names Bio 66, U-1258), or 11-oxoprogesterone, also known as pregn-4-ene-3,11,20-trione, is a pregnane steroid related to cortisone (11-keto-17α,21-dihydroxyprogesterone) that was formerly used in veterinary medicine in the treatment of bovine ketosis. It was synthesized in 1940. The steroid has profound effects on carbohydrate metabolism and possesses activities associated with adrenal cortex hormones like cortisone. However, it is non-toxic even in high dosages, suggesting that it lacks conventional glucocorticoid activity, and it does not possess mineralocorticoid activity, unlike other adrenocortical hormones. 11-Ketoprogesterone may act through membrane glucocorticoid receptors.
primaryTopic
11-Ketoprogesterone
11-Ketoprogesterone (brand name Ketogestin; former developmental code names Bio 66, U-1258), or 11-oxoprogesterone, also known as pregn-4-ene-3,11,20-trione, is a pregnane steroid related to cortisone (11-keto-17α,21-dihydroxyprogesterone) that was formerly used in veterinary medicine in the treatment of bovine ketosis. It was synthesized in 1940. The steroid has profound effects on carbohydrate metabolism and possesses activities associated with adrenal cortex hormones like cortisone. However, it is non-toxic even in high dosages, suggesting that it lacks conventional glucocorticoid activity, and it does not possess mineralocorticoid activity, unlike other adrenocortical hormones. 11-Ketoprogesterone may act through membrane glucocorticoid receptors.
has abstract
11-Ketoprogesterone (brand nam ...... dulator of the GABAA receptor.
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alternative name
Ketogestin
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CAS number
ChEMBL
FDA UNII code
9Y1Y86O4T5
PubChem
Wikipage page ID
52,622,349
page length (characters) of wiki page
Wikipage revision ID
992,491,196
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CAS number
ChEMBL
ChemSpiderID
IUPAC name
PubChem
SMILES
CC[C@H]1CC[C@@H]2[C@@]1C
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StdInChIKey
WKAVAGKRWFGIEA-DADBAOPHSA-N
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synonyms
Bio 66; U-1258; 11-Oxoprogesterone; Pregn-4-ene-3,11,20-trione
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tradename
Ketogestin
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wikiPageUsesTemplate
subject
comment
11-Ketoprogesterone (brand nam ...... rane glucocorticoid receptors.
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label
11-Ketoprogesterone
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