16α-Hydroxyandrostenedione
16α-Hydroxyandrostenedione (16α-OH-A4), also known as 16α-hydroxyandrost-4-ene-3,17-dione, is an endogenous and naturally occurring steroid and metabolic intermediate in the biosynthesis of estriol during pregnancy. It is produced from dehydroepiandrosterone (DHEA), which is converted into 16α-hydroxy-DHEA sulfate, then desulfated and aromatized into 16α-hydroxyestrone, and finally converted into estriol by 17β-hydroxysteroid dehydrogenase.
16-HA416-Hydroxy-4-androstene-3,17-dione16-Hydroxy-4-androstenedione16-Hydroxyandrost-4-ene-3,17-dione16-Hydroxyandrost-4-enedione16-Hydroxyandrostenedione16-OH-A416-OHA416-hydroxy-4-androstene-3,17-dione16-hydroxy-4-androstenedione16-hydroxyandrost-4-ene-3,17-dione16-hydroxyandrost-4-enedione16-hydroxyandrostenedione16α-HA416α-Hydroxy-4-androstene-3,17-dione16α-Hydroxy-4-androstenedione16α-Hydroxyandrost-4-ene-3,17-dione16α-Hydroxyandrost-4-enedione16α-OH-A416α-OHA416α-hydroxy-4-androstene-3,17-dione16α-hydroxy-4-androstenedione16α-hydroxyandrost-4-ene-3,17-dione16α-hydroxyandrost-4-enedione16α-hydroxyandrostenedione
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15α-Hydroxy-DHEA15α-Hydroxy-DHEA sulfate16-HA416-Hydroxy-4-androstene-3,17-dione16-Hydroxy-4-androstenedione16-Hydroxyandrost-4-ene-3,17-dione16-Hydroxyandrost-4-enedione16-Hydroxyandrostenedione16-OH-A416-OHA416-hydroxy-4-androstene-3,17-dione16-hydroxy-4-androstenedione16-hydroxyandrost-4-ene-3,17-dione16-hydroxyandrost-4-enedione16-hydroxyandrostenedione16α-HA416α-Hydroxy-4-androstene-3,17-dione16α-Hydroxy-4-androstenedione16α-Hydroxy-DHEA16α-Hydroxy-DHEA sulfate16α-Hydroxyandrost-4-ene-3,17-dione16α-Hydroxyandrost-4-enedione16α-Hydroxyestrone16α-OH-A416α-OHA416α-hydroxy-4-androstene-3,17-dione16α-hydroxy-4-androstenedione16α-hydroxyandrost-4-ene-3,17-dione16α-hydroxyandrost-4-enedione16α-hydroxyandrostenedioneC19H26O31,2-dimethoxyethaanHydroxyandrostenedioneSteroidogenesis inhibitor
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16α-Hydroxyandrostenedione
16α-Hydroxyandrostenedione (16α-OH-A4), also known as 16α-hydroxyandrost-4-ene-3,17-dione, is an endogenous and naturally occurring steroid and metabolic intermediate in the biosynthesis of estriol during pregnancy. It is produced from dehydroepiandrosterone (DHEA), which is converted into 16α-hydroxy-DHEA sulfate, then desulfated and aromatized into 16α-hydroxyestrone, and finally converted into estriol by 17β-hydroxysteroid dehydrogenase.
has abstract
16α-Hydroxyandrostenedione (16 ...... -hydroxysteroid dehydrogenase.
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alternative name
16α-Hydroxyandrost-4-ene-3,17-dione; 16α-OH-A4
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IUPAC name
(2R,3aS,3bR,9aR,9bS,11aS)-2-Hy ...... [a]phenanthrene-1,7(3bH)-dione
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52,453,584
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1,017,502,016
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16α-Hydroxyandrostenedione (16 ...... -hydroxysteroid dehydrogenase.
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label
16α-Hydroxyandrostenedione
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