The 2006 Tampa Bay Devil Rays season was their ninth since the franchise was created. They finished last in the AL East division, posting a league-worst record of 61–101. Their manager was Joe Maddon, who entered his first season with the Devil Rays. The Devil Rays' offense had the fewest runs (689), hits (1,395) and RBI (650) in Major League Baseball, as well as the joint-lowest batting average (.255) and lowest on-base percentage (.314).