2010 US Open – Women's Doubles

Serena Williams and Venus Williams were the defending champions. However, Serena withdrew from the tournament because of a foot injury and Venus chose to participate in the singles event only. Vania King and Yaroslava Shvedova defeated Liezel Huber and Nadia Petrova 2–6, 6–4, 7–6(7–4) in the final. This match was played over two days due to heavy rainfall on September 12.

2010 US Open – Women's Doubles

Serena Williams and Venus Williams were the defending champions. However, Serena withdrew from the tournament because of a foot injury and Venus chose to participate in the singles event only. Vania King and Yaroslava Shvedova defeated Liezel Huber and Nadia Petrova 2–6, 6–4, 7–6(7–4) in the final. This match was played over two days due to heavy rainfall on September 12.