The 2020 Coppa Florio or 2020 Coppa Florio Hankook 12 Hours of Sicily was the first running of the Coppa Florio since 1981. It was the fifth round of both the 2020 24H GT Series and the 2020 24H TCE Series, the fourth round of the Europe Series and was held from 9 to 11 October at the Autodromo di Pergusa. It was the first international racing series to take place at the Autodromo di Pergusa since 2012. The race was won by Frédéric Fatien, Jordan Grogor, Mathieu Jaminet and Robert Renauer. Miklas Born and Autorama Motorsport by Wolf-Power Racing secured the TCE Europe Drivers' and Teams' Championship after they won.