23S ribosomal RNA
The 23S rRNA is a 2904 nt long (in E. coli) component of the large subunit (50S) of the bacterial/archean ribosome. The ribosomal peptidyl transferase activity resides in domain V of this rRNA, and this domain is the most common binding site for antibiotics that inhibit translation. A well-known member of this antibiotic class, chloramphenicol, acts by inhibiting peptide bond formation, with recent 3D-structural studies showing two different binding sites depending on the species of ribosome. Linezolid and quinupristin-dalfopristin also bind to the 23S rRNA, and cross-resistance has been demonstrated between these antibiotics. Compared to 16S rRNA genes, 23S rRNA genes typically have higher sequence variations including insertions and/or deletions.
'The All-Species Living Tree' Project16S ribosomal RNA23S23S methyl RNA motif23S rRNA (guanine2069-N7)-methyltransferase23S rRNA (guanine2535-N1)-methyltransferase23S rRNA (uridine2479-2'-O)-methyltransferase23s rrna28S ribosomal RNA5S ribosomal RNAAcidithiobacillus caldusAcidithiobacillus thiooxidansBacterial taxonomyBacterial translationChlamydophilaChloramphenicolChristine S. ChowDNA barcodingEukaryotic large ribosomal subunit (60S)Eukaryotic ribosomeGentamicinHydrogenobacter thermophilusInternal transcribed spacerLSU rRNALactobacillus pontisLincosamidesLinezolidMT-RNR2Machine learning in bioinformaticsMacrolideMycoplasma pneumoniaeNucleic acid tertiary structurePasteurella canisPeptidyl transferasePlastid evolutionProkaryotic large ribosomal subunitRibonuclease ERibonuclease TRibosomal DNARibosomal RNA
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23S ribosomal RNA
The 23S rRNA is a 2904 nt long (in E. coli) component of the large subunit (50S) of the bacterial/archean ribosome. The ribosomal peptidyl transferase activity resides in domain V of this rRNA, and this domain is the most common binding site for antibiotics that inhibit translation. A well-known member of this antibiotic class, chloramphenicol, acts by inhibiting peptide bond formation, with recent 3D-structural studies showing two different binding sites depending on the species of ribosome. Linezolid and quinupristin-dalfopristin also bind to the 23S rRNA, and cross-resistance has been demonstrated between these antibiotics. Compared to 16S rRNA genes, 23S rRNA genes typically have higher sequence variations including insertions and/or deletions.
has abstract
23S rRNA是一个长为2904nt(在大腸桿菌中)的细菌 ...... 制肽键形成来发挥作用。利奈唑胺和也能结合于23S rRNA。
@zh
El ARN ribosomal 23S, a veces ...... eración del enlace peptídico.
@es
L'ARN ribosomique 23S est le p ...... quelle appartient le ribosome.
@fr
The 23S rRNA is a 2904 nt long ...... led by the 5.8S ribosomal RNA.
@en
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14.075.884
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1.022.246.572
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caption
Predicted secondary structure and sequence conservation of PK-G12rRNA
@en
id
RF01118
@en
name
Pseudoknot of the domain G of 23S ribosomal RNA
@en
Rfam
RF01118
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RNA type
symbol
PK-G12rRNA
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Tax domain
wikiPageUsesTemplate
subject
comment
23S rRNA是一个长为2904nt(在大腸桿菌中)的细菌 ...... 制肽键形成来发挥作用。利奈唑胺和也能结合于23S rRNA。
@zh
El ARN ribosomal 23S, a veces ...... eración del enlace peptídico.
@es
L'ARN ribosomique 23S est le p ...... quelle appartient le ribosome.
@fr
The 23S rRNA is a 2904 nt long ...... g insertions and/or deletions.
@en
label
23S ribosomal RNA
@en
23S 核糖体RNA
@zh
ARN ribosomal 23S
@es
ARN ribosomique 23S
@fr