4-Dimethylamino-4-(p-tolyl)cyclohexanone
4-Dimethylamino-4-(p-tolyl)cyclohexanone (sometimes known as dimetamine) is a narcotic analgesic with an arylcyclohexylamine chemical structure. It was developed by Daniel Lednicer at Upjohn in the 1970s. It has around the same analgesic potency as morphine, with analogues where the p-methyl group is replaced by chlorine or bromine being slightly weaker. However derivatives where the ketone group has been reacted with a Grignard reagent to add a phenethyl substitution are several hundred times stronger, and in this series it is the bromo compound BDPC that is the most potent.
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4-Dimethylamino-4-(p-tolyl)cyclohexanone
4-Dimethylamino-4-(p-tolyl)cyclohexanone (sometimes known as dimetamine) is a narcotic analgesic with an arylcyclohexylamine chemical structure. It was developed by Daniel Lednicer at Upjohn in the 1970s. It has around the same analgesic potency as morphine, with analogues where the p-methyl group is replaced by chlorine or bromine being slightly weaker. However derivatives where the ketone group has been reacted with a Grignard reagent to add a phenethyl substitution are several hundred times stronger, and in this series it is the bromo compound BDPC that is the most potent.
has abstract
4-Dimethylamino-4-(p-tolyl)cyc ...... BDPC that is the most potent.
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CAS number
65619-06-9
ChEMBL
PubChem
Wikipage page ID
62,352,058
page length (characters) of wiki page
Wikipage revision ID
1,014,170,217
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ATC prefix
None
@en
CAS number
ChEMBL
ChemSpiderID
15,036,994
drug name
DTXSID
DTXSID30503812
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IUPAC name
PubChem
12,595,643
SMILES
CC1=CC=CC2NC
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StdInChIKey
VCEODKLEIJWHMI-UHFFFAOYSA-N
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wikiPageUsesTemplate
comment
4-Dimethylamino-4-(p-tolyl)cyc ...... BDPC that is the most potent.
@en
label
4-Dimethylamino-4-(p-tolyl)cyclohexanone
@en
sameAs
isPrimaryTopicOf
name
4-Dimethylamino-4-(p-tolyl)cyclohexanone
@en