4-Fluoro-5-methoxy-DMT
4-Fluoro-5-Methoxy-N,N-dimethyltryptamine (4-F-5-MeO-DMT) was first described by David E. Nichols team in 2000. It is a potent 5-HT1A agonist. Substitution with the 4-fluorine markedly increased 5-HT1A selectivity over 5-HT2A/2C receptors with potency greater than that of the 5-HT1A agonist 8-OH-DPAT. The analog compound with the N,N-dialkyl substituents constrained into a pyrrolidine ring, is a slightly stronger agonist for the 5-HT1A receptor and retains the selectivity over the 5-HT2A/2C receptors.
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4-Fluoro-5-methoxy-DMT
4-Fluoro-5-Methoxy-N,N-dimethyltryptamine (4-F-5-MeO-DMT) was first described by David E. Nichols team in 2000. It is a potent 5-HT1A agonist. Substitution with the 4-fluorine markedly increased 5-HT1A selectivity over 5-HT2A/2C receptors with potency greater than that of the 5-HT1A agonist 8-OH-DPAT. The analog compound with the N,N-dialkyl substituents constrained into a pyrrolidine ring, is a slightly stronger agonist for the 5-HT1A receptor and retains the selectivity over the 5-HT2A/2C receptors.
has abstract
4-Fluoro-5-Methoxy-N,N-dimethy ...... over the 5-HT2A/2C receptors.
@en
CAS number
312314-18-4
PubChem
Wikipage page ID
28,358,100
page length (characters) of wiki page
Wikipage revision ID
964,545,128
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CAS number
ChemSpiderID
IUPAC name
PubChem
10,082,834
SMILES
CNCCC1=CNC2=C1CF
@en
StdInChIKey
CTEKFOKTEGQYLO-UHFFFAOYSA-N
@en
verifiedrevid
451,563,257
wikiPageUsesTemplate
comment
4-Fluoro-5-Methoxy-N,N-dimethy ...... over the 5-HT2A/2C receptors.
@en
label
4-Fluoro-5-methoxy-DMT
@en