53rd Brigade or 53rd Infantry Brigade may refer to: * 53rd Brigade (Greece) of the Greek Army during the Greek Civil War * 53rd Indian Brigade of the British Indian Army in the First World War * 53rd Indian Infantry Brigade of the British Indian Army in the Second World War * 53rd Brigade (United Kingdom) of the British Army during the First and Second World Wars * 53rd Mountain Motorized Infantry Brigade (People's Republic of China) * 53rd Anti-Aircraft Rocket Brigade of the Russian Ground Forces * 53rd Mechanized Brigade (Ukraine) * 53rd Infantry Brigade Combat Team (United States)