6-APT
6-(2-Aminopropyl)tetralin (6-APT), also sometimes called tetralinylaminopropane (TAP), is a drug of the amphetamine class which acts as a selective serotonin releasing agent (SSRA). It has IC50 values of 121 nM, 6,436 nM, and 3,371 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively. Though it possesses an appreciable in vitro profile, in animal drug discrimination studies it was not found to substitute for MMAI or amphetamine and to only partially substitute for MBDB. This parallels Alexander Shulgin's finding that EDMA (the 1,4-benzodioxine analogue of 6-APT) is inactive, and appears to indicate that the pharmacokinetics of both EDMA and 6-APT may not be favorable.
1-(6-Tetralinyl)-2-aminopropane1-(6-Tetralinyl)-2-propanamine1-(6-Tetralinyl)-2-propylamine1-(6-Tetralinyl)propan-2-amine1-(6-tetralinyl)-2-aminopropane1-(6-tetralinyl)-2-propanamine1-(6-tetralinyl)-2-propylamine1-(6-tetralinyl)propan-2-amine6-(2-Aminopropyl)tetralin6-Tetralinyl-2-aminopropane6-Tetralinylpropan-2-amine6-tetralinyl-2-aminopropane6-tetralinylpropan-2-amineAminopropyltetralinPropylaminotetralinTetralinylaminopropaneTetralinylisopropanamineTetralinylisopropylamine
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1-(6-Tetralinyl)-2-aminopropane1-(6-Tetralinyl)-2-propanamine1-(6-Tetralinyl)-2-propylamine1-(6-Tetralinyl)propan-2-amine1-(6-tetralinyl)-2-aminopropane1-(6-tetralinyl)-2-propanamine1-(6-tetralinyl)-2-propylamine1-(6-tetralinyl)propan-2-amine5-APDI6-(2-Aminopropyl)tetralin6-Tetralinyl-2-aminopropane6-Tetralinylpropan-2-amine6-tetralinyl-2-aminopropane6-tetralinylpropan-2-amineAminopropyltetralinC13H19NList of psychedelic drugsNaphthylaminopropanePropylaminotetralinSerotonin releasing agentSubstituted methylenedioxyphenethylamineTH-PVPTetralinylaminopropaneTetralinylisopropanamineTetralinylisopropylamine
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6-APT
6-(2-Aminopropyl)tetralin (6-APT), also sometimes called tetralinylaminopropane (TAP), is a drug of the amphetamine class which acts as a selective serotonin releasing agent (SSRA). It has IC50 values of 121 nM, 6,436 nM, and 3,371 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively. Though it possesses an appreciable in vitro profile, in animal drug discrimination studies it was not found to substitute for MMAI or amphetamine and to only partially substitute for MBDB. This parallels Alexander Shulgin's finding that EDMA (the 1,4-benzodioxine analogue of 6-APT) is inactive, and appears to indicate that the pharmacokinetics of both EDMA and 6-APT may not be favorable.
has abstract
6-(2-Aminopropyl)tetralin (6-A ...... nd 6-APT may not be favorable.
@en
CAS number
ChEMBL
FDA UNII code
F26UB8P44X
PubChem
Wikipage page ID
27,167,142
page length (characters) of wiki page
Wikipage revision ID
992,458,600
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ATC prefix
none
@en
CAS number
ChEMBL
ChemSpiderID
23,204,045
IUPAC name
legal status
Uncontrolled
@en
PubChem
14,964,398
routes of administration
SMILES
CCN
@en
StdInChIKey
UTVKUFYOPJCDPE-UHFFFAOYSA-N
@en
UNII
F26UB8P44X
@en
verifiedrevid
451,350,040
wikiPageUsesTemplate
hypernym
comment
6-(2-Aminopropyl)tetralin (6-A ...... nd 6-APT may not be favorable.
@en
label
6-APT
@en