80th Regiment or 80th Infantry Regiment may refer to: * 80th Regiment of Foot (Royal Edinburgh Volunteers), a unit of the British Army, 1778–1783 * 80th Regiment of Foot (Staffordshire Volunteers), a unit of the British Army * 80th Airmobile Regiment (Ukraine), a unit of the Ukrainian Army * 80th Infantry Regiment (Imperial Japanese Army), a unit of the Japanese Army * 80th Training Regiment (United States) a unit of the United States Army ReserveAmerican Civil War regiments * 80th Illinois Volunteer Infantry Regiment, a unit of the Union (North) Army * 80th Indiana Infantry Regiment, a unit of the Union (North) Army * 80th New York Volunteer Infantry Regiment, a unit of the Union (North) Army * 80th Ohio Infantry, a unit of the Union (North) Army * 80th United States Colored Inf