APOBEC
APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like") is a family of evolutionarily conserved cytidine deaminases. A mechanism of generating protein diversity is mRNA editing. Members of this family are C-to-U editing enzymes. The N-terminal domain of APOBEC like proteins is the catalytic domain, while the C-terminal domain is a pseudocatalytic domain. More specifically, the catalytic domain is a zinc dependent cytidine deaminase domain and is essential for cytidine deamination. RNA editing by APOBEC-1 requires homodimerisation and this complex interacts with RNA binding proteins to form the editosome.
5-MethylcytosineAPOBEC1APOBEC3GAPOBEC3HAPOBEC4Activation-induced cytidine deaminaseAdaptive immunity in jawless fish1,2-dimethoxyethaanDNA demethylationDRIP-seqInterferon gammaKataegisMissense mRNAMutational signaturesPOLD1ReprogrammingTRIM5alphaTheodora HatziioannouViral infectivity factorViral quasispecies
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APOBEC
APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like") is a family of evolutionarily conserved cytidine deaminases. A mechanism of generating protein diversity is mRNA editing. Members of this family are C-to-U editing enzymes. The N-terminal domain of APOBEC like proteins is the catalytic domain, while the C-terminal domain is a pseudocatalytic domain. More specifically, the catalytic domain is a zinc dependent cytidine deaminase domain and is essential for cytidine deamination. RNA editing by APOBEC-1 requires homodimerisation and this complex interacts with RNA binding proteins to form the editosome.
has abstract
APOBEC ("apolipoprotein B mRNA ...... idely studied APOBEC3G's page.
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APOBEC (apolipoprotein B mRNA ...... teractúa con para formar el .
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APOBEC est l'acronyme anglopho ...... iaison à l'ARN pour former l'.
@fr
Цитидиндезамінази, APOBEC — ро ...... BEC наявні у хребетних тварин.
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Symbol
Wikipage page ID
17,875,920
page length (characters) of wiki page
Wikipage revision ID
993,815,100
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InterPro
IPR007904
@en
IPR013158
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name
APOBEC-like C-terminal domain
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APOBEC-like N-terminal domain
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Pfam
PF05240
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PF08210
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symbol
APOBEC_C
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APOBEC_N
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wikiPageUsesTemplate
subject
hypernym
comment
APOBEC ("apolipoprotein B mRNA ...... roteins to form the editosome.
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APOBEC (apolipoprotein B mRNA ...... as conservada en la evolución.
@es
APOBEC est l'acronyme anglopho ...... à-dire de Cytidine en Uridine.
@fr
Цитидиндезамінази, APOBEC — ро ...... BEC наявні у хребетних тварин.
@uk
label
APOBEC
@en
APOBEC
@es
APOBEC
@fr
Цитидиндезамінази
@uk