Acetyl-CoA carboxylase
Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is a multi-subunit enzyme in most prokaryotes and in the chloroplasts of most plants and algae, whereas it is a large, multi-domain enzyme in the cytoplasm of most eukaryotes. The most important function of ACC is to provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification. The human genome contains the genes for two different ACCs—ACACA and ACACB.
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(acetyl-CoA carboxylase)-phosphatase(acetyl-CoA carboxylase) kinase3-Hydroxypropionate bicycleACACAACACBACCACCDACCaseACOT1ACOT11ACOT13ACOT2ACOT4ACOT6AMP-activated protein kinaseAcca1,2-dimethoxyethaanAcetyl-CoA:carbon-dioxide ligase (ADP-forming)Acetyl-coa carboxylaseAcetyl CoA carboxylaseAcetyl coa carboxylaseAcetyl coenzyme A carboxylaseActive siteAcyl-CoA thioesterase 9AdipocyteAgaric acidAquatic Species Program1,2-dimethoxyethaanBiotin carboxyl carrier proteinBiotin carboxylaseBotanyC2orf81Carbamoyl phosphate synthetaseCarboxylationCarnitineCarnitine palmitoyltransferase ICitric acidCitric acid cycleCoenzyme ADe novo synthesis
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Acetyl-CoA carboxylase
Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is a multi-subunit enzyme in most prokaryotes and in the chloroplasts of most plants and algae, whereas it is a large, multi-domain enzyme in the cytoplasm of most eukaryotes. The most important function of ACC is to provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification. The human genome contains the genes for two different ACCs—ACACA and ACACB.
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Acetyl-CoA carboxylase (ACC) i ...... ifferent ACCs—ACACA and ACACB.
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1,009,819,869
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Acetyl-CoA carboxylase
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Acetyl-CoA carboxylase (ACC) i ...... ifferent ACCs—ACACA and ACACB.
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Acetyl-CoA carboxylase
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Acetyl-CoA carboxylase
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