Acute megakaryoblastic leukemia
Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues. Megakaryoblasts are the most immature precursor cells in a platelet-forming lineage; they mature to promegakaryocytes and, ultimately, megakaryocytes which cells shed membrane-enclosed particles, i.e. platelets, into the circulation. Platelets are critical for the normal clotting of blood. While malignant megakaryoblasts usually are the predominant proliferating and tissue-damaging cells, their similarly malignant descendants, promegakaryocytes and megakaryocytes, are variable contributors to the malignancy.
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AMKLAML-M7Acute myeloid leukemiaAcute myeloid leukemia M7CD34Down syndromeFHL2GATA1GPR31Hematologic diseaseInternational Classification of Diseases for OncologyLeukemiaList of diseases (A)List of hematologic conditionsMKL1Mediastinal germ cell tumorMyelodysplastic syndromeMyeloid leukemiaTMEM241Transient myeloproliferative disease
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Acute megakaryoblastic leukemia
Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues. Megakaryoblasts are the most immature precursor cells in a platelet-forming lineage; they mature to promegakaryocytes and, ultimately, megakaryocytes which cells shed membrane-enclosed particles, i.e. platelets, into the circulation. Platelets are critical for the normal clotting of blood. While malignant megakaryoblasts usually are the predominant proliferating and tissue-damaging cells, their similarly malignant descendants, promegakaryocytes and megakaryocytes, are variable contributors to the malignancy.
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Acute megakaryoblastic leukemi ...... e AML-M7 category of leukemia.
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La leucemia megacarioblastica ...... i, i percusori dei trombociti.
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La leucémie aiguë mégacaryocyt ...... ettaire, les mégacaryoblastes.
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Острый мегакариобластный лейко ...... азу и электронной микроскопии.
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ابيضاض أرومة النواءات الحاد Ac ...... به أكثر من 1% من مجمل الحالات.
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16,187,658
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1,010,144,071
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AML-M7, bone marrow section
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D007947
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Acute megakaryoblastic leukemia
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Acute megakaryoblastic leukemi ...... ontributors to the malignancy.
@en
La leucemia megacarioblastica ...... i, i percusori dei trombociti.
@it
La leucémie aiguë mégacaryocyt ...... ettaire, les mégacaryoblastes.
@fr
Острый мегакариобластный лейко ...... ии ФАБ он относится к типу М7.
@ru
ابيضاض أرومة النواءات الحاد Ac ...... ض دم نقوي حاد غير مُحدد الفئة.
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label
Acute megakaryoblastic leukemia
@en
Leucemia megacarioblastica acuta
@it
Leucémie aiguë mégacaryocytaire
@fr
Острый мегакариобластный лейкоз
@ru
ابيضاض أرومة النواءات الحاد
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Acute megakaryoblastic leukemia
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