Acute promyelocytic leukemia
Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene and is distinguished from other forms of AML by its responsiveness to all-trans retinoic acid (ATRA; also known as tretinoin) therapy. Acute promyelocytic leukemia was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness, with a median survival time of less than a week. Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 80-90% according to one study.
Wikipage disambiguates
7+3 (chemotherapy)AML-M3APLAPMLAasia IshaqueActinidia polygamaAcute Promyelocytic LeukemiaAcute Promyelocytic Myelogenous LeukemiaAcute Promyeloid LeukaemiaAcute myeloid leukemiaAcute myeloid leukemia with t(15;17)Acute promyelocytic leukaemiaAnne Dejean-AssématArsenicArsenic biochemistryArsenic_trioxideArsenicin AAuer rodBlood Cancer UKChemotherapy regimenChen SaijuanChildhood leukemiaChromosomal translocationChuck PaganoDana BibleDifferentiation therapyDisseminated intravascular coagulationEbolaFIP1L1Faggot cellFeline sarcoma oncogeneFowler's solutionGirish R GowdaGreek Fire (band)HK3HL60Hedgehog pathway inhibitorsHouse (season 5)Hugues de ThéIchikawa Danjūrō XII
Link from a Wikipage to another Wikipage
leader
primaryTopic
Acute promyelocytic leukemia
Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene and is distinguished from other forms of AML by its responsiveness to all-trans retinoic acid (ATRA; also known as tretinoin) therapy. Acute promyelocytic leukemia was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness, with a median survival time of less than a week. Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 80-90% according to one study.
has abstract
Acute promyelocytenleukemie is ...... ffectieve behandeling bestond.
@nl
Acute promyelocytic leukemia ( ...... 80-90% according to one study.
@en
La leucemia promielocítica agu ...... ácido transretinoico (ATRA).
@es
La leucémie aiguë promyélocyta ...... FAB elle correspond à la LAM3.
@fr
Leucemia promielocítica aguda ...... do all-trans retinóico (ATRA).
@pt
Ostra białaczka promielocytowa ...... orych w wieku od 20 do 50 lat.
@pl
Per leucemia promielocitica ac ...... un quadro genetico specifico.
@it
Острый промиелоцитарный лейкоз ...... сирования приблизительно 70 %.
@ru
اللوكيميا الحادة بخلايا النخاع ...... من التدهور يقدر ب70% تقريباً.
@ar
DiseasesDB
eMedicine subject
med
@en
eMedicine topic
34
@en
ICD10
MeSH ID
OMIM id
Link from a Wikipage to an external page
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
1.020.882.966
Link from a Wikipage to another Wikipage
caption
Bone marrow smear from a patie ...... locyte with multiple Auer rods
@en
DiseasesDB
eMedicineSubj
med
@en
eMedicineTopic
field
Hematology and oncology
@en
image size
MeshID
D015473
@en
name
Acute promyelocytic leukemia
@en
OMIM
Orphanet
SNOMED CT
28.950.004
wikiPageUsesTemplate
wordnet_type
subject
hypernym
comment
Acute promyelocytenleukemie is ...... de respons op (ATRA) therapie.
@nl
Acute promyelocytic leukemia ( ...... 80-90% according to one study.
@en
La leucemia promielocítica agu ...... stadounidense-británica FAB.
@es
La leucémie aiguë promyélocyta ...... FAB elle correspond à la LAM3.
@fr
Leucemia promielocítica aguda ...... do all-trans retinóico (ATRA).
@pt
Ostra białaczka promielocytowa ...... orych w wieku od 20 do 50 lat.
@pl
Per leucemia promielocitica ac ...... un quadro genetico specifico.
@it
Острый промиелоцитарный лейкоз ...... вой кислотой и триоксидом мышь
@ru
اللوكيميا الحادة بخلايا النخاع ...... من التدهور يقدر ب70% تقريباً.
@ar
label
Acute promyelocytenleukemie
@nl
Acute promyelocytic leukemia
@en
Leucemia promielocitica acuta
@it
Leucemia promielocítica aguda
@es
Leucemia promielocítica aguda
@pt
Leucémie aiguë promyélocytaire
@fr
Ostra białaczka promielocytowa
@pl
Promyelozytenleukämie
@de
Острый промиелоцитарный лейкоз
@ru
لوكيميا حادة بخلايا النخاع الخديج
@ar
sameAs
wasDerivedFrom
isPrimaryTopicOf
name
Acute promyelocytic leukemia
@en