Aldosterone synthase
Aldosterone synthase, also called steroid 18-hydroxylase, corticosterone 18-monooxygenase or P450C18, is a steroid hydroxylase cytochrome P450 enzyme involved in the biosynthesis of the mineralocorticoid aldosterone and other steroids. The enzyme catalyzes sequential hydroxylations of the steroid angular methyl group at C18 after initial 11β-hydroxylation (the enzyme has steroid 18-hydroxylase activity as well as steroid 11 beta-hydroxylase activity). It is encoded by CYP11B2 gene in humans.
1,2-dimethoxyethaan11β-Hydroxyprogesterone18-Hydroxy-11-deoxycorticosterone18-Hydroxycorticosterone18-Hydroxycortisol18-Hydroxylase18-Hydroxylase deficiency18-hydroxylase18-hydroxylase deficiency18-hydroxylationAdrenal cortexAdrenal gland1,2-dimethoxyethaanAldosterone synthase deficiencyAldosterone synthetase deficiencyAminoglutethimideApparent mineralocorticoid excess syndromeCYP11B2CYP11B2 (gene)CYP11B3CYP11 familyChromosome 8Corticosteroid1,2-dimethoxyethaanCytochrome P450Estrogen-related receptor alphaGlucocorticoid remediable aldosteronismGlutamic acidHypoaldosteronismInborn errors of steroid metabolismList of MeSH codes (D08)List of MeSH codes (D12.776)List of OMIM disorder codesList of cytochrome P450 modulatorsList of diseases (0–9)List of human protein-coding genes 1MespirenoneMetabotropic glutamate receptorMitotaneOsilodrostat
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Aldosterone synthase
Aldosterone synthase, also called steroid 18-hydroxylase, corticosterone 18-monooxygenase or P450C18, is a steroid hydroxylase cytochrome P450 enzyme involved in the biosynthesis of the mineralocorticoid aldosterone and other steroids. The enzyme catalyzes sequential hydroxylations of the steroid angular methyl group at C18 after initial 11β-hydroxylation (the enzyme has steroid 18-hydroxylase activity as well as steroid 11 beta-hydroxylase activity). It is encoded by CYP11B2 gene in humans.
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Aldosterone synthase, also cal ...... te balance and blood pressure.
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Aldosterone synthase, also cal ...... ded by CYP11B2 gene in humans.
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Aldosterone synthase
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