Alveolar rhabdomyosarcoma
Alveolar rhabdomyosarcoma (ARMS) is a subtype of the rhabdomyosarcoma soft tissue cancer family whose lineage is from mesenchymal cells and are related to skeletal muscle cells. ARMS tumors resemble the alveolar tissue in the lungs. Tumor location varies from patient to patient, but is commonly found in the head and neck region, male and female urogenital tracts, the torso, and extremities. Two fusion proteins can be associated with ARMS, but are not necessary, PAX3-FKHR (now known as FOXO1). and PAX7-FKHR. In children and adolescents ARMS accounts for about 1 percent of all malignancies, has an incidence rate of 1 per million, and most cases occur sporadically with no genetic predisposition. PAX3-FOXO1 is now known to drive cancer-promoting gene expression programs through creation of dis
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ArmsAutopsy (House)Embryonal rhabdomyosarcomaFibroblast growth factor receptor 1Forkhead box protein O1Jamie Allen (priest)List of MeSH codes (C04)List of OMIM disorder codesList of diseases (R)List of medical abbreviations: APAX3PAX7PhysochlainaRMST (gene)RhabdomyosarcomaRhabdomyosarcoma, alveolarXAGE1D
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Alveolar rhabdomyosarcoma
Alveolar rhabdomyosarcoma (ARMS) is a subtype of the rhabdomyosarcoma soft tissue cancer family whose lineage is from mesenchymal cells and are related to skeletal muscle cells. ARMS tumors resemble the alveolar tissue in the lungs. Tumor location varies from patient to patient, but is commonly found in the head and neck region, male and female urogenital tracts, the torso, and extremities. Two fusion proteins can be associated with ARMS, but are not necessary, PAX3-FKHR (now known as FOXO1). and PAX7-FKHR. In children and adolescents ARMS accounts for about 1 percent of all malignancies, has an incidence rate of 1 per million, and most cases occur sporadically with no genetic predisposition. PAX3-FOXO1 is now known to drive cancer-promoting gene expression programs through creation of dis
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Alveolar rhabdomyosarcoma (ARM ...... ements called super enhancers.
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ORPHA
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D018232
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name
Alveolar rhabdomyosarcoma
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SNOMED CT
404,053,004
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Alveolar rhabdomyosarcoma (ARM ...... ograms through creation of dis
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Alveolar rhabdomyosarcoma
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Alveolar rhabdomyosarcoma
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