The Amphisbatinae was a small subfamily of moths in the superfamily Gelechioidea. Like their relatives therein, their exact relationships are not yet very well resolved. The present lineage is often included in the Depressariinae as a tribe Amphisbatini, though more often within the context of a "splitting" approach to Gelechioidea systematics and taxonomy, wherein the Depressariinae are elevated to full family rank and the Amphisbatinae are treated as a subfamily therein. An even more extremely split-up layout even treats the Amphisbatinae as full family Amphisbatidae. In the scheme used here, the Amphisbatinae are included in the Oecophoridae as a subfamily alongside the Depressariinae.