Anfinsen's dogma
Anfinsen's dogma, also known as the thermodynamic hypothesis, is a postulate in molecular biology. It states that, at least for a small globular protein in its standard physiological environment, the native structure is determined only by the protein's amino acid sequence. The dogma was championed by the Nobel Prize Laureate Christian B. Anfinsen from his research on the folding of ribonuclease A. The postulate amounts to saying that, at the environmental conditions (temperature, solvent concentration and composition, etc.) at which folding occurs, the native structure is a unique, stable and kinetically accessible minimum of the free energy. In other words, there are three conditions for formation of a unique protein structure:
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Anfinsen's DogmaBovine pancreatic ribonucleaseChaperone (protein)Christian B. AnfinsenDecoyDenaturation (biochemistry)Folding funnelGene expressionIntrinsically disordered proteinsLevinthal's paradoxList of biophysicistsMolecular biophysicsMonessen,_PennsylvaniaPOEM@HomeProtein dynamicsProtein foldingProtein structureThermodynamic hypothesis
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Anfinsen's dogma
Anfinsen's dogma, also known as the thermodynamic hypothesis, is a postulate in molecular biology. It states that, at least for a small globular protein in its standard physiological environment, the native structure is determined only by the protein's amino acid sequence. The dogma was championed by the Nobel Prize Laureate Christian B. Anfinsen from his research on the folding of ribonuclease A. The postulate amounts to saying that, at the environmental conditions (temperature, solvent concentration and composition, etc.) at which folding occurs, the native structure is a unique, stable and kinetically accessible minimum of the free energy. In other words, there are three conditions for formation of a unique protein structure:
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Anfinsen's dogma, also known a ...... her high order conformations).
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Das Anfinsen-Dogma (auch therm ...... an Ribonuklease A formuliert.
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Il dogma di Anfinsen, conosciu ...... vada incontro al ripiegamento.
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アンフィンセンのドグマ（英: Anfinsen's dogm ...... 造のような）非常に複雑な形状の変化を伴わないことを意味する。
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Anfinsen's dogma, also known a ...... of a unique protein structure:
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Das Anfinsen-Dogma (auch therm ...... an Ribonuklease A formuliert.
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Il dogma di Anfinsen, conosciu ...... e e cineticamente accessibile.
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アンフィンセンのドグマ（英: Anfinsen's dogm ...... ニークなタンパク質構造を形成するには、次の3つの条件がある。
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Anfinsen's dogma
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Anfinsen-Dogma
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Dogma di Anfinsen
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アンフィンセンのドグマ
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