Antiochus is a 1721 tragedy by the British writer John Mottley. The play is set in Ancient Greece, revolving round the relationship between Stratonice of Syria and Seleucus I Nicator and his son Antiochus I Soter, the leaders of the Seleucid Empire. The original Lincoln's Inn Fields cast included James Quin as Selecus, Lacy Ryan as Antiochus, John Egleton as Arsaces, Richard Diggs as Cleartes, Anthony Boheme as Nicanor, as Semandra and Anna Maria Seymour as Stratonice.