In asymmetric addition of dialkylzinc compounds to aldehydes dialkyl zinc compounds can be used to perform asymmetric additions to aldehydes, generating substituted alcohols as products (See Barbier reaction). Chiral alcohols are prevalent in many natural products, drugs, and other important organic molecules. Dimethyl zinc is often used with an asymmetric amino alcohol, amino thiol, or other ligand to affect enantioselective additions to aldehydes and ketones. One of the first examples of this process, reported by Noyori and colleagues, features the use of the amino alcohol ligand (−)-3-exo-dimethylaminoisobornenol along with dimethylzinc to add a methyl group asymmetrically to benzaldehyde (see figure). Many ligands have been developed for binding zinc during addition reactions. TADDOLs