Barnase
Barnase (a portmanteau of "BActerial" "RiboNucleASE") is a bacterial protein that consists of 110 amino acids and has ribonuclease activity. It is synthesized and secreted by the bacterium Bacillus amyloliquefaciens, but is lethal to the cell when expressed without its inhibitor barstar. The inhibitor binds to and occludes the ribonuclease active site, preventing barnase from damaging the cell's RNA after it has been synthesized but before it has been secreted. The barnase/barstar complex is noted for its extraordinarily tight protein-protein binding, with an on-rate of 108s−1M−1.
primaryTopic
Barnase
Barnase (a portmanteau of "BActerial" "RiboNucleASE") is a bacterial protein that consists of 110 amino acids and has ribonuclease activity. It is synthesized and secreted by the bacterium Bacillus amyloliquefaciens, but is lethal to the cell when expressed without its inhibitor barstar. The inhibitor binds to and occludes the ribonuclease active site, preventing barnase from damaging the cell's RNA after it has been synthesized but before it has been secreted. The barnase/barstar complex is noted for its extraordinarily tight protein-protein binding, with an on-rate of 108s−1M−1.
has abstract
Barnasa (Un portmanteau de "BA ...... con una tasa de of 108s−1M−1.
@es
Barnase (a portmanteau of "BAc ...... with an on-rate of 108s−1M−1.
@en
La barnase est une ribonucléas ...... s du repliement des protéines.
@fr
La barnasi (nome originato dal ...... issociazione pari a 108s−1M−1.
@it
Барна́за — бактериальный белок ...... белковых комплексов в природе.
@ru
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994,402,073
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caption
The tightly bound complex betw ...... nd barstar is colored in blue.
@en
ECnumber
name
Barnase
@en
PDB supplemental
symbol
Barnase
@en
UniProt
P00648
@en
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hypernym
comment
Barnasa (Un portmanteau de "BA ...... con una tasa de of 108s−1M−1.
@es
Barnase (a portmanteau of "BAc ...... with an on-rate of 108s−1M−1.
@en
La barnase est une ribonucléas ...... directement dans la catalyse.
@fr
La barnasi (nome originato dal ...... issociazione pari a 108s−1M−1.
@it
Барна́за — бактериальный белок ...... белковых комплексов в природе.
@ru
label
Barnasa
@es
Barnase
@en
Barnase
@fr
Barnasi
@it
Барназа
@ru
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isPrimaryTopicOf
name
Barnase
@en