Bartolomeo Guidiccioni (1470 – 4 November 1549) was an Italian Roman Catholic bishop and cardinal. He was one of the closest collaborators of Cardinal Alessandro Farnese, both as Bishop of Parma and afterwards when he became Pope Paul III. He served the pope as Vicar of Rome, and Prefect of the Tribunal of the Signature of Justice, as well as a member of several ad hoc commissions of cardinals. He was Bishop of Teramo (1539–1542) and Bishop of Lucca (1546–1549). He was one of the organizers and leading officers of the Council of Trent.