The Battle of Siemiatycze was one of the largest battles of the January Uprising. It took place on February 6–7, 1863, in the town of Siemiatycze, Russian Empire (now Poland). Russian forces of some 2,500 under General Zachar Maniukin clashed with 4,000 Polish insurgents commanded by , Roman Roginski and Wladyslaw Cichorski-Zameczek. The battle was won by the Russians, and their victory had widespread implications in the area of Białystok, as local population decided not to back the uprising.