Isabella Ayre (born 9 December 1998) is a former Australian rules footballer who played for the Carlton Blues and Brisbane Lions in the AFL Women's competition. Ayre played state league football with Bendigo prior to the creation of the AFL Women's competition. Ayre was recruited by Carlton with the number 51 pick in the 2016 AFL Women's draft. She made her debut in the Blues' inaugural game against Collingwood at Princes Park on 3 February 2017. On 25 May 2017, Ayre was, along with Nat Exon, traded to Brisbane in a complex trade involving four teams, five players and a draft pick.