Bik Kwoon Yeung Tye (Chinese: 戴楊碧瓘; born c. 1947) is a Chinese-American molecular geneticist and structural biologist. Tye's pioneering work on eukaryotic DNA replication led to the discovery of the minichromosome maintenance (MCM) genes in 1984, which encode the catalytic core of the eukaryotic replisome. Tye also determined the first high-resolution structures of both the MCM complex and the Origin Recognition Complex (ORC) in 2015 and 2018. Tye is currently a Professor Emeritus (2015) at Cornell University and a visiting professor at the Hong Kong University of Science & Technology. She is married to Henry Sze-Hoi Tye and is the mother of Kay Tye and Lynne Tye.