Boceprevir
Boceprevir (INN, trade name Victrelis) is a protease inhibitor used to treat hepatitis caused by hepatitis C virus (HCV) genotype 1. It binds to the HCV nonstructural protein 3 active site. It was initially developed by Schering-Plough, then by Merck after it acquired Schering in 2009. It was approved by the FDA in May 2011. In January 2015, Merck announced that they would be voluntarily withdrawing Victrelis from the market due to the overwhelming superiority of newer direct-acting antiviral agents, such as ledipasvir/sofosbuvir.
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ATC code J05ATC code J05AE12ATCvet code QJ05AE12Antimicrobial peptidesAsunaprevirC27H45N5O51,2-dimethoxyethaanDesogestrelDonald JensenDrug reaction with eosinophilia and systemic symptomsHepatitisHepatitis C virusInterferonList of antiviral drugsList of drugs: Bi–BoNS3 (HCV)NarlaprevirProtease inhibitor (pharmacology)TelaprevirVictrelis
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Boceprevir
Boceprevir (INN, trade name Victrelis) is a protease inhibitor used to treat hepatitis caused by hepatitis C virus (HCV) genotype 1. It binds to the HCV nonstructural protein 3 active site. It was initially developed by Schering-Plough, then by Merck after it acquired Schering in 2009. It was approved by the FDA in May 2011. In January 2015, Merck announced that they would be voluntarily withdrawing Victrelis from the market due to the overwhelming superiority of newer direct-acting antiviral agents, such as ledipasvir/sofosbuvir.
has abstract
Boceprevir (INN, trade name Vi ...... such as ledipasvir/sofosbuvir.
@en
Boceprevir (nome comercial Vic ...... provado em 13 de maio de 2011.
@pt
Boceprevir es un medicamento a ...... tis C crónica, serotipo 1.
@es
Boceprevir ist ein virenhemmen ...... . Boceprevir ist oral wirksam.
@de
Il boceprevir (INN, nome comme ...... le in Italia dall'aprile 2013.
@it
Le bocéprévir est un inhibiteu ...... ins de la moitié des patients.
@fr
Боцепревір — синтетичний проти ...... алення FDA у травні 2011 року.
@uk
alternative name
Victrelis
@en
CAS number
394730-60-0
ChEMBL
DrugBank
FDA UNII code
89BT58KELH
KEGG
MedlinePlus
PubChem
Wikipage page ID
17,145,945
page length (characters) of wiki page
Wikipage revision ID
993,058,125
Link from a Wikipage to another Wikipage
ATC prefix
J05
@en
ATC suffix
AP03
@en
CAS number
ChEMBL
ChemSpiderID
DrugBank
DB08873
@en
elimination half-life
IUPAC name
-N-[3-Amino-1--2,3-dioxopropyl ...... clo[3.1.0]hexane-2-carboxamide
@en
IUPHAR ligand
KEGG
D08876
@en
legal US
Rx-only
@en
licence EU
yes
@en
licence US
Boceprevir
@en
MedlinePlus
a611039
@en
NIAID ChemDB
pregnancy US
X
@en
protein bound
PubChem
10,324,367
routes of administration
Oral
@en
SMILES
O=C[C@@H]CC
@en
StdInChIKey
LHHCSNFAOIFYRV-DOVBMPENSA-N
@en
tradename
Victrelis
@en
Verifiedfields
changed
@en
verifiedrevid
461,592,659
Watchedfields
changed
@en
wikiPageUsesTemplate
hypernym
comment
Boceprevir (INN, trade name Vi ...... such as ledipasvir/sofosbuvir.
@en
Boceprevir (nome comercial Vic ...... , com os medicamentos citados.
@pt
Boceprevir es un medicamento a ...... tis C crónica, serotipo 1.
@es
Boceprevir ist ein virenhemmen ...... . Boceprevir ist oral wirksam.
@de
Il boceprevir (INN, nome comme ...... le in Italia dall'aprile 2013.
@it
Le bocéprévir est un inhibiteu ...... ins de la moitié des patients.
@fr
Боцепревір — синтетичний проти ...... алення FDA у травні 2011 року.
@uk