CD47
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers, and more recently, for the treatment of pulmonary fibrosis.
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ACAMPsAnti-CD47Antigens, cd47BNIP3CD-47CD47 (gene)1,2-dimethoxyethaanCancer immunotherapyCd47 antigensHsp90IAPInduced pluripotent stem cellInduced stem cellsK. Christopher GarciaList of MeSH codes (D12.776.395)List of MeSH codes (D12.776.543)List of MeSH codes (D23)List of human clusters of differentiationList of human protein-coding genes 1MUL1Non-catalytic tyrosine-phosphorylated receptorNovimmunePhagoptosisSignal-regulatory proteinSignal-regulatory protein alphaThrombospondinThrombospondin 1Tumor microenvironment
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CD47
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers, and more recently, for the treatment of pulmonary fibrosis.
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CD47 (Cluster of Differentiati ...... ors has been reported as well.
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CD47 (Cluster of Differentiati ...... eatment of pulmonary fibrosis.
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CD47
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