CD79
CD79 (Cluster of Differentiation 79) is a transmembrane protein that forms a complex with the B-cell receptor (BCR) and generates a signal following recognition of antigen by the BCR. CD79 is composed of two distinct chains called CD79A and CD79B (also known as Igα and Igβ); these form a heterodimer on the surface of a B cell stabilized by disulfide bonding. CD79a and CD79b are both members of the immunoglobulin superfamily. Human CD79a is encoded by the mb-1 gene that is located on chromosome 19, and CD79b is encoded by the B29 gene that located on chromosome 17. Both CD79 chains contain an immunoreceptor tyrosine-based activation motif (ITAM) in their intracellular tails that they use to propagate a signal in a B cell, in a similar manner to CD3-generated signal transduction observed dur
Wikipage redirect
Antigens, cd79B-cell receptorCd79 antigensDiffuse large B-cell lymphomaFollicular hyperplasiaFollicular lymphomaHumoral immune deficiencyINPP5DImmunoglobulin superfamilyImmunoreceptor tyrosine-based activation motifIntravascular lymphomasList of MeSH codes (D12.776)List of MeSH codes (D12.776.124)List of MeSH codes (D12.776.543)List of MeSH codes (D23)List of primary immunodeficienciesOutline of immunology
Link from a Wikipage to another Wikipage
primaryTopic
CD79
CD79 (Cluster of Differentiation 79) is a transmembrane protein that forms a complex with the B-cell receptor (BCR) and generates a signal following recognition of antigen by the BCR. CD79 is composed of two distinct chains called CD79A and CD79B (also known as Igα and Igβ); these form a heterodimer on the surface of a B cell stabilized by disulfide bonding. CD79a and CD79b are both members of the immunoglobulin superfamily. Human CD79a is encoded by the mb-1 gene that is located on chromosome 19, and CD79b is encoded by the B29 gene that located on chromosome 17. Both CD79 chains contain an immunoreceptor tyrosine-based activation motif (ITAM) in their intracellular tails that they use to propagate a signal in a B cell, in a similar manner to CD3-generated signal transduction observed dur
has abstract
CD79 (Cluster of Differentiati ...... eceptor activation on T cells.
@en
OMIM id
RefSeq
Symbol
Wikipage page ID
10,246,676
page length (characters) of wiki page
Wikipage revision ID
993,685,080
Link from a Wikipage to another Wikipage
AltSymbols
IG-alpha
@en
IG-beta
@en
Arm
q
@en
RefSeq
NM_001783
@en
NM_021602
@en
UniProt
P11912
@en
P40259
@en
wikiPageUsesTemplate
subject
hypernym
comment
CD79 (Cluster of Differentiati ...... gnal transduction observed dur
@en
label
CD79
@en
wasDerivedFrom
isPrimaryTopicOf
name
CD79a molecule, immunoglobulin-associated alpha
@en
CD79b molecule, immunoglobulin-associated beta
@en