Casey Powell (born February 18, 1976) is an American former college and professional lacrosse player from West Carthage, New York. In 1998, he graduated from Syracuse University, where he was a four-time USILA All-American. Powell was the NCAA Division I Most Outstanding Player in 1997 and 1998. Powell was inducted into the National Lacrosse Hall of Fame in 2017. His two younger brothers, Ryan and Mikey, were also lacrosse stars at Syracuse, where they all wore jersey number 22.