Ced-9
Cell death abnormality gene 9 (CED-9), also known as apoptosis regulator CED-9, is a gene found in Caenorhabditis elegans that inhibits/represses programmed cell death (apoptosis). The gene was discovered while searching for mutations in the apoptotic pathway after the discovery of the apoptosis promoting genes CED-3 and CED-4. The gene gives rise to the apoptosis regulator CED-9 protein found as an Integral membrane protein in the mitochondrial membrane. The protein is homologous to the human apoptotic regulator Bcl-2 as well as all other proteins in the Bcl-2 protein family. CED-9 is involved in the inhibition of CED-4 which is the activator of the CED-3 caspase. Because of the pathway homology with humans as well as the specific protein homology, CED-9 has been used to represent the hum
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Ced-9
Cell death abnormality gene 9 (CED-9), also known as apoptosis regulator CED-9, is a gene found in Caenorhabditis elegans that inhibits/represses programmed cell death (apoptosis). The gene was discovered while searching for mutations in the apoptotic pathway after the discovery of the apoptosis promoting genes CED-3 and CED-4. The gene gives rise to the apoptosis regulator CED-9 protein found as an Integral membrane protein in the mitochondrial membrane. The protein is homologous to the human apoptotic regulator Bcl-2 as well as all other proteins in the Bcl-2 protein family. CED-9 is involved in the inhibition of CED-4 which is the activator of the CED-3 caspase. Because of the pathway homology with humans as well as the specific protein homology, CED-9 has been used to represent the hum
has abstract
Cell death abnormality gene 9 ...... ractions of Bcl-2 in research.
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Wikipage page ID
17,288,194
page length (characters) of wiki page
Wikipage revision ID
986,561,193
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Chromosome
III
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EntrezChromosome
BX284603
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EntrezGene
GenLoc end
10,337,080
GenLoc start
10,335,172
HomoloGene
name
CED-9
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Organism
Caenorhabditis elegans
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RefSeqmRNA
NM_066883
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RefSeqProtein
NP_499284
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symbol
CED-9
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taxId
UniProt
P41958
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wikiPageUsesTemplate
subject
comment
Cell death abnormality gene 9 ...... been used to represent the hum
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label
Ced-9
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