The Chamber of Commerce Building is a historic office building located at Baltimore, Maryland, United States. It is a Renaissance Revival-style of architecture with a brown glazed brick building five floors in height, eleven bays long on the west/east sides, facing Commerce Street on the west and Custom House Avenue to the east. Three bays wide (north/south) on the Water Street side, and rebuilt 1904–1905, using still standing walls / facades. It was built during the rebuilding of the old financial district in Downtown Baltimore following the Great Baltimore Fire of Sunday/Monday, February 7–8, 1904 (third worst conflagration to ever hit an American city) and features many terra cotta decorative elements. The rebuilt structure was designed by well-known Baltimore architect Charles E. Casse