The Cherokee Path (or Keowee path) was the primary route of English and Scots traders from Charleston to Columbia, South Carolina in Colonial America. It was the way they reached Cherokee towns and territories along the upper Keowee River and its tributaries. In its lower section it was known as the Savannah River. They referred to these towns along the Keowee and Tugaloo rivers (in modern Georgia) as the Lower Towns, in contrast to the Middle Towns in Western North Carolina and the Overhill Towns in present-day southeastern Tennessee west of the Appalachian Mountains.