Chlormethine
Chlormethine (INN, BAN), also known as mechlorethamine (USAN, USP), mustine, HN2, and (in post-Soviet states) embikhin (эмбихин), is a nitrogen mustard sold under the brand name Mustargen among others. It is the prototype of alkylating agents, a group of anticancer chemotherapeutic drugs. It works by binding to DNA, crosslinking two strands and preventing cell duplication. It binds to the N7 nitrogen on the DNA base guanine. As the chemical is a blister agent, its use is strongly restricted within the Chemical Weapons Convention where it is classified as a Schedule 1 substance.
1942 in science1946 in scienceABVDATC code L01ATC code L01AA05ATCvet code QL01AA05Alkylating antineoplastic agentAllopurinolBariBis(2-chloroethyl)methylamineC5H11Cl2NCOPP (chemotherapy)Cancer and nauseaCarcinogenCaryolysinCaryolysineChemotherapyChemotherapy-induced nausea and vomitingChemotherapy regimenCloraminCornelius P. RhoadsCutaneous T cell lymphomaDeath Be Not Proud (book)December 1943DichlorenDiethylenetriamine1,2-dimethoxyethaanEPA list of extremely hazardous substancesEmbichinEpstein–Barr virus-associated lymphoproliferative diseasesExtravasation (intravenous)GenotoxicityHN1 (nitrogen mustard)HN2HN2 (nitrogen mustard)HN3 (nitrogen mustard)History of cancer chemotherapyHodgkin lymphomaIndex of oncology articles
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Chlormethine
Chlormethine (INN, BAN), also known as mechlorethamine (USAN, USP), mustine, HN2, and (in post-Soviet states) embikhin (эмбихин), is a nitrogen mustard sold under the brand name Mustargen among others. It is the prototype of alkylating agents, a group of anticancer chemotherapeutic drugs. It works by binding to DNA, crosslinking two strands and preventing cell duplication. It binds to the N7 nitrogen on the DNA base guanine. As the chemical is a blister agent, its use is strongly restricted within the Chemical Weapons Convention where it is classified as a Schedule 1 substance.
has abstract
Chloormethine, ook mechloretha ...... pas na de oorlog gepubliceerd.
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Chlormethine (INN, BAN), also ...... gen mustard alkylating agents.
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Chlorometyna, chlormetyna (łac ...... wstrzykiwań) i Valchlor (żel).
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La chlorméthine a été le premi ...... e, mais aussi en dermatologie.
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La mecloretamina, nota anche c ...... ci chemioterapici antitumorali
@it
La mecloretamina, también llam ...... ioterapia de combinación MOPP.
@es
Mechlorethamin (Stickstoff-Los ...... rd als Hydrochlorid verwendet.
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Mostarda nitrogenada 2 ou HN2, ...... ormamida e sulfeto de carbono.
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Хлорметин (лат. Chlormethinum, ...... ССР известен также как эмбихин
@ru
مكلورثامين (بالإنجليزية: Chlormethine) هو دواء يُستعمل في علاج:
* لمفوما
* فطار فطراني
@ar
alternative name
Bis(2-chloroethyl)(methyl)amine
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IUPAC name
2-Chloro-N-(2-chloroethyl)-N-methylethan-1-amine
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Skeletal formula of chlormethine
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Space-filling model of the chlormethine molecule
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Skeletal formula of mechlorethamine
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OtherNames
Bisamine
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480,478,174
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Chloormethine, ook mechloretha ...... ing van de ziekte van Hodgkin.
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Chlormethine (INN, BAN), also ...... ied as a Schedule 1 substance.
@en
Chlorometyna, chlormetyna (łac ...... wstrzykiwań) i Valchlor (żel).
@pl
La chlorméthine a été le premi ...... e, mais aussi en dermatologie.
@fr
La mecloretamina, nota anche c ...... ci chemioterapici antitumorali
@it
La mecloretamina, también llam ...... ioterapia de combinación MOPP.
@es
Mechlorethamin (Stickstoff-Los ...... rd als Hydrochlorid verwendet.
@de
Mostarda nitrogenada 2 ou HN2, ...... to de Metildietanolamônio e Cl
@pt
Хлорметин (лат. Chlormethinum, ...... ССР известен также как эмбихин
@ru
مكلورثامين (بالإنجليزية: Chlormethine) هو دواء يُستعمل في علاج:
* لمفوما
* فطار فطراني
@ar
label
Chloormethine
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Chlormethine
@en
Chlorméthine
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Chlorometyna
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Mechlorethamin
@de
Mecloretamina
@es
Mecloretamina
@it
Mostarda nitrogenada 2
@pt
Хлорметин
@ru
مكلورثامين
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