Chollas Creek is an urban creek in the city of San Diego that drains to the San Diego Bay. It is also the name of a populated area of City Heights, San Diego, California. Chollas Creek arises in Lemon Grove and La Mesa, where its four branches begin. It empties into the Bay at Barrio Logan. In 2021, the city of San Diego decided to create the Chollas Creek Regional Park along many of the undeveloped parts of the creek's branches, to make better use of these areas and to remedy a long-standing lack of parks in southeastern San Diego.