Sir Christopher Willoughby, de jure 10th Baron Willoughby de Eresby (1453 – between 1 November 1498 and 13 July 1499), was heir to his second cousin, Joan Welles, 9th Baroness Willoughby de Eresby, in her own right Lady Willoughby, as well as great-grandson and heir male to William Willoughby, 5th Baron Willoughby de Eresby. Christopher Willoughby was also heir to his elder brother, Robert Willoughby, who died unmarried and underage on 24 March 1467. He was unable to enjoy his inherited title as a result of the attainders of his cousin Joan Welles' father, Richard Welles, 7th Baron Welles, and brother, Robert Welles, 8th Baron Willoughby de Eresby.