Cobicistat
Cobicistat, sold under the brand name Tybost, is a medication for use in the treatment of human immunodeficiency virus infection (HIV/AIDS). Its major mechanism of action is through the inhibition of human CYP3A proteins. Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir, and tenofovir alafenamide.
product
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ATC code V03ATC code V03AX03ATCvet code QV03AX03Atazanavir/cobicistatC40H53N7O5S21,2-dimethoxyethaanDarunavirDarunavir/cobicistatElbasvir/grazoprevirElvitegravir/cobicistat/emtricitabine/tenofovirGS-9350Gilead_SciencesGrazoprevirIntegrase inhibitorList of antiretroviral fixed-dose combinationsList of antiviral drugsList of cytochrome P450 modulatorsList of drugs: Cm–CoManagement of HIV/AIDSTenofovir_alafenamideTybost
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Cobicistat
Cobicistat, sold under the brand name Tybost, is a medication for use in the treatment of human immunodeficiency virus infection (HIV/AIDS). Its major mechanism of action is through the inhibition of human CYP3A proteins. Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir, and tenofovir alafenamide.
has abstract
Cobicistat (INN, in de ontwikk ...... iwitten in de ingewanden remt.
@nl
Cobicistat con nombre comercia ...... do atazanavir, darunavir, y .
@es
Cobicistat ist ein Arzneistoff ...... ängerte Wirksamkeit im Körper.
@de
Cobicistat, sold under the bra ...... ir, and tenofovir alafenamide.
@en
Кобицистат, продаваемый под то ...... унавир и тенофовир алафенамид.
@ru
Кобіцистат (англ. Cobicistat) ...... ного застосування з 2014 року.
@uk
كوبيسيستات هو دواء يستخدم في ع ...... ي ستريبيلد وإيفوتاز وبرزكوبكس.
@ar
alternative name
Tybost
@en
CAS number
1004316-88-4
ChEBI
ChEMBL
DrugBank
FDA UNII code
LW2E03M5PG
KEGG
MedlinePlus
PubChem
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Wikipage page ID
29,240,014
page length (characters) of wiki page
Wikipage revision ID
1,025,141,654
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ATC prefix
V03
@en
ATC suffix
AX03
@en
CAS number
ChEBI
ChEMBL
ChemSpiderID
25,084,912
DailyMedID
Cobicistat
@en
DrugBank
DB09065
@en
IUPAC name
IUPHAR ligand
KEGG
D09881
@en
legal US
Rx-only
@en
licence EU
yes
@en
MedlinePlus
a616029
@en
PubChem
25,151,504
SMILES
CCc1ncCNCNCCNCCc5ccccc5
@en
StdInChIKey
ZCIGNRJZKPOIKD-CQXVEOKZSA-N
@en
synonyms
GS-9350
@en
tradename
Tybost
@en
UNII
LW2E03M5PG
@en
Verifiedfields
changed
@en
verifiedrevid
451,564,721
Watchedfields
changed
@en
wikiPageUsesTemplate
hypernym
comment
Cobicistat (INN, in de ontwikk ...... iwitten in de ingewanden remt.
@nl
Cobicistat con nombre comercia ...... do atazanavir, darunavir, y .
@es
Cobicistat ist ein Arzneistoff ...... ängerte Wirksamkeit im Körper.
@de
Cobicistat, sold under the bra ...... ir, and tenofovir alafenamide.
@en
Кобицистат, продаваемый под то ...... унавир и тенофовир алафенамид.
@ru
Кобіцистат (англ. Cobicistat) ...... ного застосування з 2014 року.
@uk
كوبيسيستات هو دواء يستخدم في ع ...... ي ستريبيلد وإيفوتاز وبرزكوبكس.
@ar