Combermere House, or 148 Hospital Street, is a Georgian town house in Nantwich, Cheshire, England, which dates from the mid-18th century. It is on the south side of (at SJ6561152154), near the end of the street and opposite the junction with Millstone Lane. The building has previously been known by other street numbers, including number 154. It is listed at grade II, and local historian Jane Stevenson describes it as "sheer perfection".