Complement component 1q
The complement component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together with C1r and C1s form the C1 complex. Antibodies of the adaptive immune system can bind antigen, forming an antigen-antibody complex. When C1q binds antigen-antibody complexes, the C1 complex becomes activated. Activation of the C1 complex initiates the classical complement pathway of the complement system. The antibodies IgM and all IgG subclasses except IgG4 are able to initiate the complement system.
Complement component 1qACAMPsAdiponectinAnti-dsDNA antibodiesAntibodyAntibody-dependent enhancementApolipoprotein EAureolysin1,2-dimethoxyethaanC1QAC1QBC1QCC1Q complexC1 complexC1qC1q complexC1q domainC3a (complement)CD93CIQBCIQCClassical complement pathwayComplement-dependent cytotoxicityComplement c1qComplement component 1Complement component 1QAComplement component 1QBComplement component 1QGComplement component 1rComplement component 1sComplement deficiencyComplement systemDecorinFCN1Gordon Atkinson (Canadian politician)IgA nephropathyImmune adherenceList of MeSH codes (D12.776.124)List of human protein-coding genes 1List of primary immunodeficiencies
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Complement component 1q
The complement component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together with C1r and C1s form the C1 complex. Antibodies of the adaptive immune system can bind antigen, forming an antigen-antibody complex. When C1q binds antigen-antibody complexes, the C1 complex becomes activated. Activation of the C1 complex initiates the classical complement pathway of the complement system. The antibodies IgM and all IgG subclasses except IgG4 are able to initiate the complement system.
has abstract
The complement component 1q (o ...... nitiate the complement system.
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chromosome
EntrezGene
HGNCid
locus supplementary data
OMIM id
RefSeq
Symbol
UniProt
Wikipage page ID
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Wikipage revision ID
1,022,124,379
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label
Complement component 1q
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name
complement component 1, q subcomponent, A chain
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complement component 1, q subcomponent, B chain
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complement component 1, q subcomponent, C chain
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AltSymbols
C1QG
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Arm
p
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caption
crystal structure of a collagen viii nc1 domain trimer
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Chromosome
EntrezGene
HGNCid
InterPro
IPR001073
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LocusSupplementaryData
name
C1q domain
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complement component 1, q subcomponent, A chain
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complement component 1, q subcomponent, B chain
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complement component 1, q subcomponent, C chain
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OMIM
Pfam
PF00386
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Pfam clan
CL0100
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PROSITE
PDOC00857
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RefSeq
NM_000491
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NM_015991
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NM_172369
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symbol
UniProt
P02745
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P02746
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P02747
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subject
comment
The complement component 1q (o ...... nitiate the complement system.
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