Convulsant
A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent excitotoxicity. Most convulsants are antagonists (or inverse agonists) at either the GABAA or glycine receptors, or ionotropic glutamate receptor agonists. Many other drugs may cause convulsions as a side effect at high doses (e.g. bupropion, tramadol, pethidine, dextropropoxyphene, clomipramine) but only drugs whose primary action is to cause convulsions are known as convulsants. Nerve agents such as sarin, which were developed as chemical weapons, produce convulsions as a major part of their toxidrome, but also produce a number of other effects in
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3-Mercaptopropionic acid4-MethylimidazoleAllylglycineAlstonineAminooxyacetic acidAnalepticBIDNBicyclic phosphateBrunfelsamidineCUMYL-4CN-BINACACauses of seizuresChlorodiazepamChlorophenylsilatraneCloflubicyneConvulsantsCrimidineCyclothiazideDMCMErythravineEthosuximideFG-7142FlurothylGABAA receptor negative allosteric modulatorGABA receptor antagonistHalogenated etherIPTBOIchthyothereolIndole alkaloidIsoflurothylList of MeSH codes (D27)List of benzodiazepinesMethionine sulfoximineMethyl fluoroacetateMorphine-3-glucuronideNeurosteroidNorpropoxypheneOpioid receptorPWZ-029PericinePhenylsilatrane
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Convulsant
A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent excitotoxicity. Most convulsants are antagonists (or inverse agonists) at either the GABAA or glycine receptors, or ionotropic glutamate receptor agonists. Many other drugs may cause convulsions as a side effect at high doses (e.g. bupropion, tramadol, pethidine, dextropropoxyphene, clomipramine) but only drugs whose primary action is to cause convulsions are known as convulsants. Nerve agents such as sarin, which were developed as chemical weapons, produce convulsions as a major part of their toxidrome, but also produce a number of other effects in
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A convulsant is a drug which i ...... usually classified separately.
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A convulsant is a drug which i ...... e a number of other effects in
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Convulsant
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