In statistics, the Cuzick–Edwards test is a significance test whose aim is to detect the possible clustering of sub-populations within a clustered or non-uniformly-spread overall population. Possible applications of the test include examining the spatial clustering of childhood leukemia and lymphoma within the general population, given that the general population is spatially clustered. The test is based on: An example application of this test was to spatial clustering of leukaemias and lymphomas among young people in New Zealand.