Cyclin E
Cyclin E is a member of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle that determines initiation of DNA duplication. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase.
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CCNECDKN1BCIZ1CUL4ACell cycleCell cycle analysisCell division control protein 4Centrosome cycleCyclinCyclin-dependent kinaseCyclin-dependent kinase 1Cyclin-dependent kinase 2Cyclin ACyclin DCyclin D/Cdk4Cyclin E1Cyclin eEmbryonic stem cellEndoreduplicationFBXW7FusomeG0 phaseG1/S transitionGalectinGene duplicationHippo signaling pathwayIndex of biochemistry articlesInduced cell cycle arrestList of MeSH codes (D12.776)List of MeSH codes (D23)Mir-223Mir-26 microRNA precursor familyOncovirus1,2-dimethoxyethaanParkin (ligase)RICTORRNA-induced silencing complexRetinoblastoma proteinSIM2Stem cell
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Cyclin E
Cyclin E is a member of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle that determines initiation of DNA duplication. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase.
has abstract
Cyclin E is a member of the cy ...... lowing progression to S phase.
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OMIM id
RefSeq
Symbol
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
992,582,054
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AltSymbols
CCNE
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Arm
q
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RefSeq
NM_001238
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NM_057749
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UniProt
O96020
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P24864
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wikiPageUsesTemplate
subject
hypernym
comment
Cyclin E is a member of the cy ...... lowing progression to S phase.
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label
Cyclin E
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wasDerivedFrom
isPrimaryTopicOf
name
cyclin E1
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cyclin E2
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